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Article

Genetic Modifiers of Sickle Cell Anemia Phenotype in a Cohort of Angolan Children.

Genes - 8 Apr 2024

Ginete Catarina, Delgadinho Mariana, Santos Brígida, Miranda Armandina, Silva Carina, Guerreiro Paulo, Chimusa Emile R, Brito Miguel

Abstract excerpt

The aim of this study was to identify genetic markers in the HBB Cluster; HBS1L-MYB intergenic region; and BCL11A, KLF1, FOX3, and ZBTB7A genes associated with the heterogeneous phenotypes of Sickle Cell Anemia (SCA) using next-generation sequencing, as well as to assess their influence and prevalence in an Angolan population. Hematological, biochemical, and clinical data were considered to determine patients'...

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Identifiers

PMID: 38674403
DOI: 10.3390/genes15040469
PMCID: PMC11049512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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