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Whole-exome sequencing reveals an association of rs112065068 in TGOLN2 gene with distant metastasis of non-small cell lung cancer.

Gene - 20 Aug 2024

Gerashchenko Tatiana, Skitchenko Rostislav, Korobeynikova Anastasia, Kuanysheva Kristina, Khozyainova Anna, Vorobiev Rostislav, Rodionov Evgeny, Miller Sergey, Topolnitsky Evgeny, Shefer Nikolay, Anisimenko Maxim, Zhuikova Lilia, Vashisth Mrinal, Pankova Olga, Perelmuter Vladimir, Rezapova Valeria, Artomov Mykyta, Denisov Evgeny

Abstract excerpt

Early prediction and prevention of recurring illness is critical for improving the survival rates of patients with non-small cell lung cancer (NSCLC). Previously, we demonstrated that the presence of premalignant epithelial changes in the small bronchi distant to the primary tumor is associated with NSCLC progression: isolated basal cell hyperplasia (iBCH) indicates a high risk of distant metastasis, BCH combined...

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Identifiers

PMID: 38670394
DOI: 10.1016/j.gene.2024.148507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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