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Article

Paired tumor and normal whole genome sequencing of metastatic olfactory neuroblastoma.

PloS one - 1 Jan 2012

Weiss Glen J, Liang Winnie S, Izatt Tyler, Arora Shilpi, Cherni Irene, Raju Robert N, Hostetter Galen, Kurdoglu Ahmet, Christoforides Alexis, Sinari Shripad, Baker Angela S, Metpally Raghu, Tembe Waibhav D, Phillips Lori, Von Hoff Daniel D, Craig David W, Carpten John D

Abstract excerpt

BACKGROUND: Olfactory neuroblastoma (ONB) is a rare cancer of the sinonasal tract with little molecular characterization. We performed whole genome sequencing (WGS) on paired normal and tumor DNA from a patient with metastatic-ONB to identify the somatic alterations that might be drivers of tumor...

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Identifiers

PMID: 22649506
DOI: 10.1371/journal.pone.0037029
PMCID: PMC3359355

Genes

KDR
MYC
NLRC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22649506-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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