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Article

Deep sequencing reveals the genomic characteristics of lung adenocarcinoma presenting as ground-glass nodules (GGNs)

1 Mar 2021

Abstract excerpt

Background: The concept of multi-step progression from atypical adenomatous hyperplasia (AAH) to invasive adenocarcinoma (ADC) has been proposed, and ground-glass nodules (GGNs) may play a critical role during the early lung tumorigenesis. We present the first comprehensive description of the genomic architecture of GGNs to unravel the genetic basis of GGN.Methods: We investigated 30 GGN-like lungs ADC by...

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PMID: 33889506
DOI: 10.21037/tlcr-20-1086

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