Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer.

Cancer immunology, immunotherapy : CII - 26 Apr 2024

Wang Yadong, Huang Zhicheng, Li Bowen, Xue Jianchao, Guo Chao, Bing Zhongxing, Zheng Zhibo, Song Yang, Xu Yuan, Huang Guanghua, Li Haochen, Yu Xiaoqing, Xia Yankai, Li Ruirui, Si Xiaoyan, Zhang Li, Li Ji, Song Lan, Xiong Yuanyuan, Gu Dejian, Song Mengmeng, Zhou Zhipeng, Chen Rongrong, Feng Zhe, Bie Zhixin, Li Xiaoguang, Yang Huaxia, Li Shanqing, Liang Naixin

Abstract excerpt

The increase in the detection rate of synchronous multiple primary lung cancer (MPLC) has posed remarkable clinical challenges due to the limited understanding of its pathogenesis and molecular features. Here, comprehensive comparisons of genomic and immunologic features between MPLC and solitary lung cancer nodule (SN), as well as different lesions of the same patient, were performed. Compared with SN, MPLC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Neoplasms, Multiple Primary

Share to Receptors, Antigen, T-Cell

Source

Open in PubMed Open full text

Identifiers

PMID: 38668781
DOI: 10.1007/s00262-024-03703-8
PMCID: PMC11052747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer.PMID 38668781Read ↗

Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stagesSemantic proximity Read ↗

Genomic and immune heterogeneity of multiple synchronous lung adenocarcinoma at different developmental stages.Semantic proximity Read ↗

Genomic characteristics and immune landscape of super multiple primary lung cancer.Semantic proximity Read ↗

Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.Semantic proximity Read ↗

Multi-omics analysis unveils immunosuppressive microenvironment in the occurrence and development of multiple pulmonary lung cancersSemantic proximity Read ↗

Characterization of Distinct T Cell Receptor Repertoires in Tumor and Distant Non-tumor Tissues from Lung Cancer PatientsSemantic proximity Read ↗

Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancerSemantic proximity Read ↗

Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma.Semantic proximity Read ↗

Towards the molecular era of discriminating multiple lung cancersSemantic proximity Read ↗

Genomic profiles and transcriptomic microenvironments in 2 patients with synchronous lung adenocarcinoma and lung squamous cell carcinoma: a case report.Semantic proximity Read ↗

Genetic, DNA methylation, and immune profile discrepancies between early-stage single primary lung cancer and synchronous multiple primary lung cancer.Semantic proximity Read ↗

Single‐cell dissection reveals immunosuppressive F13A1+ macrophage as a hallmark for multiple primary lung cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.