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Article

Genomic characteristics and immune landscape of super multiple primary lung cancer.

EBioMedicine - 1 Mar 2024

Yang Zhenlin, Zhou Bolun, Guo Wei, Peng Yue, Tian He, Xu Jiachen, Wang Shuaibo, Chen Xiaowei, Hu Bin, Liu Chengming, Wang Zhijie, Li Chunxiang, Gao Shugeng, He Jie

Abstract excerpt

BACKGROUND: In recent years, a growing number of patients with multiple primary lung cancer (MPLC) are being diagnosed, and a subset of these patients is found to have a large number of lesions at the time of diagnosis, which are referred to as 'super MPLC'. METHODS: Here, we perform whole exome sequencing (WES) and immunohistochemistry (IHC) analysis of PD-L1 and CD8 on 212 tumor samples from 42 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38364701
DOI: 10.1016/j.ebiom.2024.105019
PMCID: PMC10878856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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