Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer

Abstract excerpt

Dear Editor, With improvements in lung cancer screening methods, there has been a dramatic increase in the detection of multiple pulmonary nodules (PNs). In multiple primary lung cancers (MPLCs), surgery achieved a 5-year overall survival rate that varies from 27.4% to 95.8%.1 Targeted therapy has been applied to MPLC patients with different responses due to driver mutation heterogeneity.2 Meanwhile, two clinical...

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