Article
Inflammatory bowel disease and breast cancer: A two-sample bidirectional Mendelian randomization study.
Medicine - 7 Jun 2024
Guo Zihao, Xu Changyu, Fang Zhihao, Yu Xiaoxiao, Yang Kai, Liu Changxu, Ning Xinwei, Dong Zhichao, Liu Chang
Abstract excerpt
There is a correlation between IBD and breast cancer according to previous observational studies. However, so far there is no evidence to support if there is a causal relationship between these 2 diseases. We acquired comprehensive Genome-Wide Association Study (GWAS) summary data on IBD (including ulcerative colitis [UC] and Crohn disease [CD]) as well as breast cancer of completely European descent from the IEU...
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