Identification of potential novel targets for treating inflammatory bowel disease using Mendelian randomization analysis.

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) is a complex autoimmune disorder, although some medications are available for its treatment. However, the long-term efficacy of these drugs remains unsatisfactory. Therefore, there is a need to develop novel drug targets for IBD treatment. METHODS: We conducted two-sample Mendelian randomization (MR) analysis using Genome-Wide Association Study (GWAS) data to assess...

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