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Article

Functional and biological implications of clonotypic diversity among human donor-unrestricted T cells.

Immunology and cell biology - 1 Jul 2024

Maerz Megan D, Cross Deborah L, Seshadri Chetan

Abstract excerpt

T cells express a T-cell receptor (TCR) heterodimer that is the product of germline rearrangement and junctional editing resulting in immense clonotypic diversity. The generation of diverse TCR repertoires enables the recognition of pathogen-derived peptide antigens presented by polymorphic major histocompatibility complex (MHC) molecules. However, T cells also recognize nonpeptide antigens through nearly...

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Share to Clone Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38659280
DOI: 10.1111/imcb.12751
PMCID: PMC11236517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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