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Article

Towards fair and clinically relevant polygenic predictions.

Trends in genetics : TIG - 1 May 2024

Vilhjálmsson Bjarni Jóhann

Abstract excerpt

Lennon et al. recently proposed a clinical polygenic score (PGS) pipeline as part of the Electronic Medical Records and Genomics (eMERGE) network initiative. In this spotlight article we discuss the broader context for the use of PGS in preventive medicine and highlight key limitations and challenges facing their inclusion in prediction models.

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Identifiers

PMID: 38643035
DOI: 10.1016/j.tig.2024.04.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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