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Article

Genetically identified mediators associated with increased risk of stroke and cardiovascular disease in individuals with autism spectrum disorder.

Journal of psychiatric research - 1 Jun 2024

Jin Tianyu, Huang Wei, Pang Qiongyi, Cao Zheng, Xing Dalin, Guo Shunyuan, Zhang Tong

Abstract excerpt

Growing evidence suggested that individuals with autism spectrum disorder (ASD) associated with stroke and cardiovascular disease (CVD). However, the causal association between ASD and the risk of stroke and CVD remains unclear. To validate this, we performed two-sample Mendelian randomization (MR) and two-step mediation MR analyses, using relevant genetic variants sourced from the largest genome-wide association...

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Identifiers

PMID: 38640796
DOI: 10.1016/j.jpsychires.2024.04.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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