Causal relationship between attention deficit hyperactivity disorder and atherosclerosis: A bidirectional Mendelian randomization study.

Abstract excerpt

Employing a bidirectional 2-sample Mendelian Randomization (MR) approach, this study endeavors to assess the potential causal relationship between attention deficit hyperactivity disorder (ADHD) and atherosclerosis (AS). Single nucleotide polymorphism loci, associated with ADHD at a significant threshold (P < 5 × 10-8), were meticulously screened from genome-wide association studies datasets to serve as...

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• Atherosclerosis
• Attention Deficit Disorder with Hyperactivity
• Causality
• Coronary Artery Disease
• Genome-Wide Association Study