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Article

Causal relationship between attention deficit hyperactivity disorder and atherosclerosis: A bidirectional Mendelian randomization study.

Medicine - 27 Jun 2025

Hu Xin-Yue, Chen Guang-Lei, Yang Xiao-Fang, Zhang Ning

Abstract excerpt

Employing a bidirectional 2-sample Mendelian Randomization (MR) approach, this study endeavors to assess the potential causal relationship between attention deficit hyperactivity disorder (ADHD) and atherosclerosis (AS). Single nucleotide polymorphism loci, associated with ADHD at a significant threshold (P < 5 × 10-8), were meticulously screened from genome-wide association studies datasets to serve as...

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Source

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Identifiers

PMID: 40587750
DOI: 10.1097/MD.0000000000042859
PMCID: PMC12212852

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