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Article

Genetic Underpinnings of Fasting and Oral Glucose-stimulated Based Insulin Sensitivity Indices.

The Journal of clinical endocrinology and metabolism - 15 Oct 2024

Suleman Sufyan, Madsen Anne L, Ängquist Lars H, Schubert Mikkel, Linneberg Allan, Loos Ruth J F, Hansen Torben, Grarup Niels

Abstract excerpt

CONTEXT: Insulin sensitivity (IS) is an important factor in type 2 diabetes (T2D) and can be estimated by many different indices. OBJECTIVE: We aimed to compare the genetic components underlying IS indices obtained from fasting and oral glucose-stimulated plasma glucose and serum insulin levels. METHODS: We computed 21 IS indices, classified as fasting, OGTT0,120, and OGTT0,30,120 indices, using fasting and oral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38635292
DOI: 10.1210/clinem/dgae275
PMCID: PMC11479690

Genes

C2CD4A
FTO
GCK
MINDY1
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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