Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans

18 Apr 2024

Abstract excerpt

BACKGROUND: Epigenetic age estimators (clocks) are predictive of human mortality risk. However, it is not yet known whether the epigenetic age of atherosclerotic plaques is predictive for the risk of cardiovascular events. METHODS: Whole-genome DNA methylation of human carotid atherosclerotic plaques (n=485) and of blood (n=93) from the Athero-Express endarterectomy cohort was used to calculate epigenetic age...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Congenital heart defects research
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38634280
DOI: 10.1161/atvbaha.123.320692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in HumansPMID 38634280Read ↗

Atherosclerotic fibrous plaques in females are characterized by endothelial-to-mesenchymal transition and linked to smokingSemantic proximity Read ↗

Sex-Specific Regulation of Endothelial-to-Mesenchymal Transition (EndMT) During AtherosclerosisSemantic proximity Read ↗

DNA methylation dynamics in human carotid plaques after cerebrovascular events.Semantic proximity Read ↗

Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).Semantic proximity Read ↗

Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults studySemantic proximity Read ↗

Endothelial-to-mesenchymal transition gene signature derived from single-cell transcriptomics of human atherosclerotic tissue associates with stable plaque histological characteristics.Semantic proximity Read ↗

Epigenetic Regulation of Vascular DiseasesSemantic proximity Read ↗

Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular DiseaseSemantic proximity Read ↗

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.Semantic proximity Read ↗

Epigenetic Modifications as Predictive Biomarkers for Cardiovascular Disease: A Longitudinal Study on DNA Methylation Patterns and Disease RiskSemantic proximity Read ↗

Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans.Semantic proximity Read ↗

Association of cardiovascular health and epigenetic age accelerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.