Article
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).
Clinical epigenetics - 17 Jan 2022
Ammous Farah, Zhao Wei, Lin Lisha, Ratliff Scott M, Mosley Thomas H, Bielak Lawrence F, Zhou Xiang, Peyser Patricia A, Kardia Sharon L R, Smith Jennifer A
Abstract excerpt
BACKGROUND: DNA methylation, an epigenetic mechanism modulated by lifestyle and environmental factors, may be an important biomarker of complex diseases including cardiovascular diseases (CVD) and subclinical atherosclerosis. METHODS: DNA methylation in peripheral blood samples from 391 African-Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA) was assessed at baseline, and atherosclerosis...
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