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Article

Leptin receptor Gln223Arg and Lys109Arg polymorphisms may be associated with HBV-related hepatocellular carcinoma risk: A system review and meta-analysis.

Environmental toxicology - 1 Oct 2024

Dong Xiaofeng, Zou Mengjie, Li Chunxing, Luo Honglin, Zhu Shaoliang, Gong Zheng

Abstract excerpt

Increasing evidence has suggested a strong association of hepatocellular carcinoma (HCC) susceptibility and Gln223Arg (rs1137101) and Lys109Arg (rs1137100) polymorphisms in leptin receptor (LEPR) genes. To provide a quantitative assessment for such correlation, we reviewed all related systems and conducted meta-analysis for case and control researches. A literature search of Web of Science, EMBASE, PubMed, Scopus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular
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Share to Receptors, Leptin

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PMID: 38634192
DOI: 10.1002/tox.24286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Leptin receptor Gln223Arg and Lys109Arg polymorphisms may be associated with HBV-related hepatocellular carcinoma risk: A system review and meta-analysis.PMID 38634192Read ↗

Role of leptin receptor (LEPR) gene polymorphisms and haplotypes in susceptibility to hepatocellular carcinoma in subjects with chronic hepatitis B virus infection.Semantic proximity Read ↗

The Inter-Relation between Leptin Receptor (Q223R) Gene Polymorphism and the Risk of Egyptian Patients with HCC.Semantic proximity Read ↗

The LEPR K109R and Q223R Might Contribute to the Risk of NAFLD: A Meta-Analysis.Semantic proximity Read ↗

A Comprehensive Study of the Association between LEPR Gene rs1137101 Variant and Risk of Digestive System Cancers.Semantic proximity Read ↗

Correlation of Q223R and K109R polymorphisms in leptin receptor gene with susceptibility of breast cancer: A systematic review and meta-analysis.Semantic proximity Read ↗

A meta-analysis of associations of LEPR Q223R and K109R polymorphisms with Type 2 diabetes risk.Semantic proximity Read ↗

Association of LEPR gene polymorphisms with the risk of hepatitis B virus-related liver disease in Guangxi Chinese: A case-control study.Semantic proximity Read ↗

Variations in the Obesity Gene "LEPR" Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

The association between polymorphisms in the leptin receptor gene and risk of breast cancer: a systematic review and pooled analysis.Semantic proximity Read ↗

Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer.Semantic proximity Read ↗

The association between leptin receptor gene polymorphisms and type 2 diabetes mellitus: A systematic review and meta-analysis.Semantic proximity Read ↗

Association of leptin receptor Lys109Arg and Gln223Arg polymorphisms with increased risk of clear cell renal cell carcinoma.Semantic proximity Read ↗

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