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Article

Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer.

Biomolecules - 9 Oct 2023

Alfaqih Mahmoud A, Elsalem Lina, Nusier Mohamad, Mhedat Khawla, Khader Yousef, Ababneh Ebaa

Abstract excerpt

Globally, bladder cancer (BC) is one of the ten most common tumors. Obesity is a worldwide problem associated with an increased BC risk. Considering that levels of leptin and/or its receptor are often deregulated in obese individuals, we hypothesized that they could contribute to BC. To test this hypothesis, we utilized a case-control study in which 116 patients with a confirmed diagnosis of BC and 116 controls...

Topics

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Case-Control Studies
Genetic Predisposition to Disease
Leptin
Obesity
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Leptin

Regulation of Appetite and Obesity

Urinary Bladder Neoplasms

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Identifiers

PMID: 37892180
DOI: 10.3390/biom13101498
PMCID: PMC10604959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer.PMID 37892180Read ↗

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