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Article

Association of LEPR gene polymorphisms with the risk of hepatitis B virus-related liver disease in Guangxi Chinese: A case-control study.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2020

Tang Yuzhu, Zhan Lingling, Lu Yu, Chen Huaping, Qin Simeng, Liang Zhen, Li Hao, Wei Wei, Li Shan, Qin Xue

Abstract excerpt

BACKGROUND AND OBJECTIVE: Leptin receptor (LEPR) signaling inhibits apoptosis, promotes angiogenesis and proliferation, and plays a critical role in carcinogenesis. Variants of the LEPR gene may be key factors in the growth of human malignant tumors. However, the relationship between LEPR polymorphisms and hepatocellular carcinoma (HCC) has not been thoroughly investigated. Therefore, we further investigated the...

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Identifiers

PMID: 32428570
DOI: 10.1016/j.meegid.2020.104366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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