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Article

Role of leptin receptor (LEPR) gene polymorphisms and haplotypes in susceptibility to hepatocellular carcinoma in subjects with chronic hepatitis B virus infection.

Molecular diagnosis & therapy - 1 Dec 2012

Li Zhen, Yuan Weitang, Ning Shijie, Li Jie, Zhai Wenlong, Zhang Shuijun

Abstract excerpt

AIM: The reported association of the leptin receptor (LEPR) protein with hepatocellular carcinoma (HCC) carcinogenesis prompted us to evaluate whether genetic polymorphisms of the LEPR gene affect susceptibility to HCC and its clinicopathologic characteristics. METHODS: A total of 417 subjects wh...

Topics

Carcinoma, Hepatocellular
Case-Control Studies
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Haplotypes
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Single Nucleotide

Receptors, Leptin

Source

Identifiers

PMID: 23090836
DOI: 10.1007/s40291-012-0008-1

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23090836-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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