Article
Role of leptin receptor (LEPR) gene polymorphisms and haplotypes in susceptibility to hepatocellular carcinoma in subjects with chronic hepatitis B virus infection.
Molecular diagnosis & therapy - 1 Dec 2012
Li Zhen, Yuan Weitang, Ning Shijie, Li Jie, Zhai Wenlong, Zhang Shuijun
Abstract excerpt
AIM: The reported association of the leptin receptor (LEPR) protein with hepatocellular carcinoma (HCC) carcinogenesis prompted us to evaluate whether genetic polymorphisms of the LEPR gene affect susceptibility to HCC and its clinicopathologic characteristics. METHODS: A total of 417 subjects who were diagnosed with HCC and 551 age- and sex-matched subjects without HCC were enrolled in this study. All subjects...
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