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Article

A meta-analysis of associations of LEPR Q223R and K109R polymorphisms with Type 2 diabetes risk.

PloS one - 1 Jan 2018

Yang Yunzhong, Niu Tianhua

Abstract excerpt

BACKGROUND: Leptin receptor (LEPR) plays a pivotal role in the control of body weight, energy metabolism, and insulin sensitivity. Various genetic association studies were performed to evaluate associations of LEPR genetic variants with type 2 diabetes (T2D) susceptibility. METHODS: A comprehensive search was conducted to identify all eligible case-control studies for examining the associations of LEPR single...

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Share to Diabetes Mellitus, Type 2
Share to LEPR gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, Leptin

Source

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Identifiers

PMID: 29293570
DOI: 10.1371/journal.pone.0189366
PMCID: PMC5749718

Genes

LEPR

Variants

Provenance

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