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Article

Diffuse Pleural Mesotheliomas with Genomic Near-Haploidization: A Newly Recognized Subset with Distinct Clinical, Histologic, and Molecular Features.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2024

Yang Soo-Ryum, Jayakumaran Gowtham, Benhamida Jamal, Febres-Aldana Christopher A, Fanaroff Rachel, Chang Jason, Gedvilaite Erika, Villafania Liliana B, Sauter Jennifer L, Offin Michael, Zauderer Marjorie G, Ladanyi Marc

Abstract excerpt

PURPOSE: Diffuse pleural mesotheliomas (DPM) with genomic near-haploidization (GNH) represent a novel subtype first recognized by The Cancer Genome Atlas project; however, its clinicopathologic and molecular features remain poorly defined. EXPERIMENTAL DESIGN: We analyzed clinical genomic profiling data from 290 patients with DPM using the Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable...

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Identifiers

PMID: 38630790
DOI: 10.1158/1078-0432.CCR-24-0085
PMCID: PMC11216861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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