Article
Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease.
Blood - 28 Jun 2018
Abla Oussama, Jacobsen Eric, Picarsic Jennifer, Krenova Zdenka, Jaffe Ronald, Emile Jean-Francois, Durham Benjamin H, Braier Jorge, Charlotte Frédéric, Donadieu Jean, Cohen-Aubart Fleur, Rodriguez-Galindo Carlos, Allen Carl, Whitlock James A, Weitzman Sheila, McClain Kenneth L, Haroche Julien, Diamond Eli L
Abstract excerpt
Rosai-Dorfman-Destombes disease (RDD) is a rare non-Langerhans cell histiocytosis characterized by accumulation of activated histiocytes within affected tissues. RDD, which now belongs to the R group of the 2016 revised histiocytosis classification, is a widely heterogeneous entity with a range of clinical phenotypes occurring in isolation or in association with autoimmune or malignant diseases. Recent studies...
Topics
- Adrenal Cortex Hormones
- Biopsy
- Disease Management
- Genetic Predisposition to Disease
- Histiocytes
- Histiocytosis, Sinus
- Humans
- Immunotherapy
- Mutation