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Article

Histiocytic neoplasms in the era of personalized genomic medicine.

Current opinion in hematology - 1 Jul 2016

Durham Benjamin H, Diamond Eli L, Abdel-Wahab Omar

Abstract excerpt

PURPOSE OF REVIEW: Since the discovery of B-Raf proto-oncogene (BRAF) V600E mutations in histiocytic neoplasms, diverse kinase alterations have been uncovered in BRAF V600E-wildtype histiocytoses. The purpose of this review is to outline recent molecular advances in histiocytic neoplasms and discuss their impact on the pathogenesis and treatment of these disorders. RECENT FINDINGS: Activating kinase alterations...

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Source

Open in PubMed Open full text

Identifiers

PMID: 27101528
DOI: 10.1097/MOH.0000000000000256
PMCID: PMC5112586

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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