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Article

Analysis of SIRT1 Gene SNPs and Clinical Characteristics in Medication-Related Osteonecrosis of the Jaw.

International journal of molecular sciences - 25 Mar 2024

Bojtor Bence, Vaszilko Mihaly, Armos Richard, Tobias Balint, Podani Janos, Szentpeteri Szofia, Balla Bernadett, Lengyel Balazs, Piko Henriett, Illes Anett, Kiss Andras, Putz Zsuzsanna, Takacs Istvan, Kosa Janos P, Lakatos Peter

Abstract excerpt

Certain genetic factors, including single-nucleotide polymorphisms (SNPs) in the SIRT1 gene, have been linked to medication-related osteonecrosis of the jaw (MRONJ). This study examined four SNPs in the SIRT1 gene and implemented multivariate statistical analysis to analyze genetic and clinical factors in MRONJ patients. Genomic DNA was isolated from peripheral blood samples of 63 patients of European origin...

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Identifiers

PMID: 38612458
DOI: 10.3390/ijms25073646
PMCID: PMC11011248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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