Article
Value of Serum Sirtuin-1 (SIRT1) Levels and SIRT1 Gene Variants in Periodontitis Patients.
Medicina (Kaunas, Lithuania) - 12 May 2022
Kriaučiūnas Albertas, Liutkevičienė Rasa, Gedvilaitė Greta, Kaikarytė Kristė, Vilkevičiūtė Alvita, Gleiznys Darius, Pacauskienė Ingrida, Žekonis Gediminas
Abstract excerpt
Background and Objectives: Periodontitis is a multifactorial inflammatory disease associated with biofilm dysbiosis and is defined by progressive periodontium destruction. Genes largely regulate this entire process. SIRTs are a group of histone deacetylases (HDACs) intimately involved in cell metabolism and are responsible for altering and regulating numerous cell functions. Understanding SIRTs and their...
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