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Article

GPNMB Biomarker Levels in GBA1 Carriers with Lewy Body Disorders.

Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2024

Brody Eliza M, Seo Yunji, Suh EunRan, Amari Noor, Hartstone Whitney G, Skrinak R Tyler, Zhang Hanwen, Diaz-Ortiz Maria E, Weintraub Daniel, Tropea Thomas F, Van Deerlin Vivianna M, Chen-Plotkin Alice S

Abstract excerpt

BACKGROUND: The GPNMB single-nucleotide polymorphism rs199347 and GBA1 variants both associate with Lewy body disorder (LBD) risk. GPNMB encodes glycoprotein nonmetastatic melanoma protein B (GPNMB), a biomarker for GBA1-associated Gaucher's disease. OBJECTIVE: The aim of this study was to determine whether GPNMB levels (1) differ in LBD with and without GBA1 variants and (2) associate with rs199347 genotype....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38610104
DOI: 10.1002/mds.29773
PMCID: PMC11209810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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