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Article

Germline genetic variability in pancreatic cancer risk and prognosis.

Seminars in cancer biology - 1 Feb 2022

Gentiluomo Manuel, Canzian Federico, Nicolini Andrea, Gemignani Federica, Landi Stefano, Campa Daniele

Abstract excerpt

Pancreatic cancer (PC), particularly its most common form, pancreatic ductal adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk factors could in the long term contribute to early diagnosis and mortality reduction. We review the current status of research on germline genetic factors for PC risk. Genome-wide association studies (GWAS) successfully identified common loci...

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Source

Identifiers

PMID: 32818625
DOI: 10.1016/j.semcancer.2020.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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