Article
Clinicopathologic and Molecular Characterization of Xanthomatous Giant Cell Renal Cell Carcinomas: Further Support for a Close Morphologic Spectrum to Eosinophilic Solid and Cystic Renal Cell Carcinomas.
The American journal of surgical pathology - 1 Jun 2024
Xu Yuemei, Zhang Xue, Xia Qiuyuan, Zhou Yuning, Wang Xiaotong, Fang Ru, Wang Ya, Tong Qi, Chen Jieyu, Shi Jiong, Fu Yao, Rao Qiu
Abstract excerpt
A recent study described a rare subtype of tuberous sclerosis complex ( TSC )-mutated renal cell carcinoma primarily characterized by Xanthomatous giant cell morphology. Only 2 cases in young individuals have been reported so far, making the correct diagnosis challenging from a pathological perspective. It remains unknown whether this tumor represents an independent subtype or belongs to other TSC -mutated...
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