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Article

Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson's disease.

Frontiers in immunology - 1 Jan 2024

Kulski Jerzy K, Suzuki Shingo, Shiina Takashi, Pfaff Abigail L, Kõks Sulev

Abstract excerpt

Introduction: Parkinson's disease (PD) is a neurodegenerative and polygenic disorder characterised by the progressive loss of neural dopamine and onset of movement disorders. We previously described eight SINE-VNTR-Alu (SVA) retrotransposon-insertion-polymorphisms (RIPs) located and expressed within the Human Leucocyte Antigen (HLA) genomic region of chromosome 6 that modulate the differential co-expression of 71...

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Identifiers

PMID: 38590523
DOI: 10.3389/fimmu.2024.1349030
PMCID: PMC10999589

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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