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Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expression in the Central Nervous System

2023-12-26

Abstract excerpt

Transposable elements (TEs) are repetitive elements which make up around 45% of the human genome. A class of TEs known as SINE-VNTR-Alu (SVA) demonstrate the capacity to mobilise throughout the genome, resulting in SVA polymorphisms for presence or absence within the population. Although studies have previously highlighted the involvement of TEs within neurodegenerative diseases, such as Parkinson’s disease and am...

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Literature Corpus work
4ce0259d-642a-59c7-9f0a-3a866adb2e26
DOI
10.20944/preprints202312.1981.v1
Open publication

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Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expression in the Central Nervous SystemDOI 10.20944/preprints202312.1981.v1
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