Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new association test based on disease allele selection for case-control genome-wide association studies.

BMC genomics - 12 May 2014

Chen Zhongxue

Abstract excerpt

BACKGROUND: Current robust association tests for case-control genome-wide association study (GWAS) data are mainly based on the assumption of some specific genetic models. Due to the richness of the genetic models, this assumption may not be appropriate. Therefore, robust but powerful association approaches are desirable. RESULTS: In this paper, we propose a new approach to testing for the association between the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Case-Control Studies
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 24886381
DOI: 10.1186/1471-2164-15-358
PMCID: PMC4059871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new association test based on disease allele selection for case-control genome-wide association studies.PMID 24886381Read ↗

An efficient weighted tag SNP-set analytical method in genome-wide association studies.Semantic proximity Read ↗

A powerful hybrid approach to select top single-nucleotide polymorphisms for genome-wide association study.Semantic proximity Read ↗

A powerful and robust test in genetic association studies.Semantic proximity Read ↗

Probability theory-based SNP association study method for identifying susceptibility loci and genetic disease models in human case-control data.Semantic proximity Read ↗

Rare variants analysis by risk-based variable-threshold method.Semantic proximity Read ↗

Recessive/dominant model: Alternative choice in case-control-based genome-wide association studies.Semantic proximity Read ↗

Comparisons of case-selection approaches based on allele sharing and/or disease severity index: application to the GAW14 simulated data.Semantic proximity Read ↗

Powerful statistical method to detect disease associated genes using publicly available GWAS summary dataSemantic proximity Read ↗

Detecting associated single-nucleotide polymorphisms on the X chromosome in case control genome-wide association studies.Semantic proximity Read ↗

Statistical power of model selection strategies for genome-wide association studies.Semantic proximity Read ↗

A robust method for testing association in genome-wide association studies.Semantic proximity Read ↗

Design and analysis of multiple diseases genome-wide association studies without controls.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.