Article
Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis.
Annals of clinical microbiology and antimicrobials - 5 Apr 2024
Choi Yu Jeong, Kim Yoonjung, Park Hye Jung, Kim Dokyun, Lee Hyukmin, Kim Young Ah, Lee Kyung-A
Abstract excerpt
BACKGROUND: The prevalence of multidrug-resistant tuberculosis (MDR-TB) among Korean tuberculosis patients is about 4.1%, which is higher than the OECD average of 2.6%. Inadequate drug use and poor patient compliance increase MDR-TB prevalence through selective pressure. Therefore, prompt detection of drug resistance in tuberculosis patients at the time of diagnosis and quantitative monitoring of these resistant...
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