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Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis.

Clinical chemistry - 5 Mar 2026

O'Sullivan Denise M, Jones Gerwyn M, Zolnir-Dovc Manca, Phillips Richard, Arthur Rejoice, Mtafya Bariki, Mapamba Daniel Adon, Cirillo Daniela Maria, Augustynowicz-Kopeć Ewa, Ho Mei Mei, Dagg Belinda, Friedrich Sven O, Colavita Francesca, Vulcano Antonella, Asare Prince, Yeboah-Manu Dorothy, McHugh Timothy D, Huggett Jim F

Abstract excerpt

BACKGROUND: Diagnosis of tuberculosis (TB) and multidrug-resistant tuberculosis (MDR-TB) is increasingly performed using molecular tools that detect Mycobacterium tuberculosis DNA. To ensure accurate and reliable results from the molecular tests, appropriate quality assessment is required. This involves implementing reference measurement procedures (RMPs) to characterize material standards that are representative...

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PMID: 41499263
DOI: 10.1093/clinchem/hvaf178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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