From evolutionary genetics to human immunology: how selection shapes host defence genes.

Abstract excerpt

Pathogens have always been a major cause of human mortality, so they impose strong selective pressure on the human genome. Data from population genetic studies, including genome-wide scans for selection, are providing important insights into how natural selection has shaped immunity and host defence genes in specific human populations and in the human species as a whole. These findings are helping to delineate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computational Biology
• Share to Epistasis, Genetic
• Share to Evolution, Molecular