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Article

Multiple phenotype association tests based on sliced inverse regression.

BMC bioinformatics - 4 Apr 2024

Sun Wenyuan, Jon Kyongson, Zhu Wensheng

Abstract excerpt

BACKGROUND: Joint analysis of multiple phenotypes in studies of biological systems such as Genome-Wide Association Studies is critical to revealing the functional interactions between various traits and genetic variants, but growth of data in dimensionality has become a very challenging problem in the widespread use of joint analysis. To handle the excessiveness of variables, we consider the sliced inverse...

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Identifiers

PMID: 38575890
DOI: 10.1186/s12859-024-05731-8
PMCID: PMC10996256

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