Article
Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line.
Human cell - 1 Jul 2024
Laus Ana Carolina, Gomes Izabela Natalia Faria, da Silva Aline Larissa Virginio, da Silva Luciane Sussuchi, Milan Mirella Baroni, AparecidaTeixeira Silvia, Martin Ana Carolina Baptista Moreno, do Nascimento Braga Pereira Letícia, de Carvalho Carlos Eduardo Barbosa, Crovador Camila Souza, de Paula Flávia Escremin, Nascimento Flávia Caroline, de Freitas Helder Teixeira, de Lima Vazquez Vinicius, Reis Rui Manuel, da Silva-Oliveira Renato José
Abstract excerpt
Cutaneous squamous cell carcinoma (cSCC) is a common type of skin cancer that can result in significant morbidity, although it is usually well-managed and rarely metastasizes. However, the lack of commercially available cSCC cell lines hinders our understanding of this disease. This study aims to establish and characterize a new metastatic cSCC cell line derived from a Brazilian patient. A tumor biopsy was taken...
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