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Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders

24 Dec 2021

Abstract excerpt

Epidemiological and clinical studies have suggested comorbidity between schizophrenia and several neurodegenerative disorders. However, little is known whether there exists shared genetic architecture. To explore their relationship from a genetic and transcriptomic perspective, we applied polygenic and linkage disequilibrium-informed methods to examine the genetic correlation between schizophrenia and amyotrophic...

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PMID: 35004692
DOI: 10.3389/fcell.2021.797072

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