Article
Revised HLA-DP TCE-Core Permissiveness Model Better Defines Relapse Risk and Survival following Haploidentical Transplant.
Transplantation and cellular therapy - 1 Jun 2024
Solomon Scott R, Aubrey Michael T, Bachier-Rodriguez Lizamarie, Solh Melhem M, Jackson Katelin C, Zhang Xu, Roark Christina L, Holland H Kent, Morris Lawrence E, Bashey Asad
Abstract excerpt
The presence of an HLA-DPB1 nonpermissive mismatch (NPMM) by the TCE-3 model has been associated with improved survival following haploidentical donor transplantation (HIDT) using post-transplantation cyclophosphamide (PTCy). With the development of a revised model (TCE-Core) that further separates TCE-3 "group 3" alleles into "core" (C) and "noncore" (NC) alleles, a formerly permissive mismatch (PMM) resulting...
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