Article
The impact of donor-specific anti-human leukocyte antigen antibodies in salvage haploidentical hematopoietic cell transplantation with posttransplant cyclophosphamide in patients with nonmalignant disorders.
HLA - 1 Jun 2021
Lima Alberto Cardoso Martins, Bonfim Carmem, Getz Joselito, Dornelles Luciana Nasser, do Amaral Geovana Borsato, Petterle Ricardo Rasmussen, Loth Gisele, Nabhan Samir Kanaan, Pereira Noemi Farah, Pasquini Ricardo
Abstract excerpt
The presence of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSAs) has been recognized as a major risk factor for graft failure (GF) after haploidentical hematopoietic cell transplantation with posttransplant cyclophosphamide (haplo-PTCy). However, the role of DSAs in salvage haplo-PTCy for rescuing patients with nonmalignant disorders (NMDs) has not yet been reported. The present study...
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