Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin B12 status and folic acid supplementation influence mitochondrial heteroplasmy levels in mice

15 Mar 2024

Abstract excerpt

One-carbon metabolism is a complex network of metabolic reactions that are essential for cellular function including DNA synthesis. Vitamin B12 and folate are micronutrients that are utilized in this pathway and their deficiency can result in the perturbation of one-carbon metabolism and subsequent perturbations in DNA replication and repair. This effect has been well characterized in nuclear DNA but to date,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Folate and B Vitamins Research
Share to Metabolism and Genetic Disorders
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38560530
DOI: 10.1093/pnasnexus/pgae116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin B12 status and folic acid supplementation influence mitochondrial heteroplasmy levels in micePMID 38560530Read ↗

Vitamin B12 status and folic acid supplementation influence mitochondrial heteroplasmy levels in mice as they ageSemantic proximity Read ↗

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in miceSemantic proximity Read ↗

Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.Semantic proximity Read ↗

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.Semantic proximity Read ↗

High-throughput single-cell analysis reveals progressive mitochondrial DNA mosaicism throughout life.Semantic proximity Read ↗

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.Semantic proximity Read ↗

Mitochondrial DNA Variations Modulate Alveolar Epithelial Mitochondrial Function and Oxidative Stress in Newborn Mice Exposed to HyperoxiaSemantic proximity Read ↗

Mitochondrial heteroplasmy disrupts osteoclast differentiation and bone resorption by impairing respiratory complex ISemantic proximity Read ↗

Mitochondrial dysfunction reshapes methyl-group allocation in skeletal muscleSemantic proximity Read ↗

Mitochondrial Heteroplasmy.Semantic proximity Read ↗

Brain–body mitochondrial distribution patterns lack coherence and point to tissue-specific regulatory mechanismsSemantic proximity Read ↗

Mutagenicity of folic acid deficiency and supplementation is tissue-specific and results in distinct mutation profilesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.