Article
Brain–body mitochondrial distribution patterns lack coherence and point to tissue-specific regulatory mechanisms
2 Apr 2025
Abstract excerpt
Abstract Energy transformation capacity is generally assumed to be a coherent individual trait driven by genetic and environmental factors. This predicts that some individuals should have consistently high, while others show consistently low mitochondrial oxidative phosphorylation (OxPhos) capacity across organ systems. Here, we test this assumption using multi-tissue molecular and enzymatic assays in mice and...
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