Article
Effects of intrinsically disordered regions in gp120 underlying HIV neutralization phenotypes.
Biochemical and biophysical research communications - 21 May 2024
Li Yi, Yang Li, Yang Li-Quan
Abstract excerpt
HIV envelope protein gp120 is considered a primary molecular determinant of viral neutralization phenotype due to its critical role in viral entry and immune evasion. The intrinsically disordered regions (IDRs) in gp120 are responsible for their extensive sequence variations and significant structural rearrangements. Despite HIV neutralization phenotype and sequence/structural information of gp120 have been...
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