Article
Bone Morphogenic Proteins in Pediatric Diffuse Midline Gliomas: How to Make New Out of Old?
International journal of molecular sciences - 15 Mar 2024
Berthelot Clément, Huchedé Paul, Bertrand-Chapel Adrien, Beuriat Pierre-Aurélien, Leblond Pierre, Castets Marie
Abstract excerpt
The BMP pathway is one of the major signaling pathways in embryonic development, ontogeny and homeostasis, identified many years ago by pioneers in developmental biology. Evidence of the deregulation of its activity has also emerged in many cancers, with complex and sometimes opposing effects. Recently, its role has been suspected in Diffuse Midline Gliomas (DMG), among which Diffuse Intrinsic Pontine Gliomas...
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