Article
Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?
International journal of molecular sciences - 14 Mar 2024
Lacka Katarzyna, Maciejewski Adam, Jarecki Piotr, Herman Waldemar, Lacki Jan K, Żaba Ryszard, Kowalczyk Michał J
Abstract excerpt
(1) Autoimmune thyroiditis (AIT) is the most common cause of primary hypothyroidism and one of the most frequent organ-specific autoimmune diseases. Its pathogenesis is polygenic and still requires further research. The aim of the study was to assess, for the first time in the Caucasian population, the role of selected TPO gene promoter polymorphisms (rs2071399 G/A, rs2071400C/T, rs2071402 A/G, and rs2071403 A/G)...
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