Article
Association of Thyroid Peroxidase Gene Polymorphisms and Serum Anti- TPO Levels in Egyptian Patients with Autoimmune Hypothyroidism.
Endocrine, metabolic & immune disorders drug targets - 1 Jan 2021
Ahmed Hanan S, Nsrallah Ayman A M, Abdel-Fatah Azza H, Mahmoud Amira A, Fikry Abeer A
Abstract excerpt
BACKGROUND: Thyroid peroxidase (TPO) gene mutation leads to a change in enzyme built structure resulting in the anti-TPO autoantibodies production that may cause thyroid destruction. AIM: To evaluate the association of three single nucleotide polymorphisms (SNPs) of the TPO gene and anti-TPO levels in Egyptian patients with autoimmune hypothyroidism and correlate them with the disease severity. METHODS: Two...
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