Article
Determination of IL-6 Gene Promoter Polymorphism in Patients with Hepatitis C and Its Impact on RNA Secondary Structure.
Medicina (Kaunas, Lithuania) - 22 Feb 2024
Sadiq Sarah, Anwar Mohammad Zeeshan, Shafique Huma, Manzoor Syed Mohsin, Shoaib Shaiza, Hamid Rabia, Hashmi Shoaib Naiyer, Ashraf Naeem Mahmood, Afsar Tayyaba, Bhat Mashooq Ahmad, Razak Suhail
Abstract excerpt
Background and Objectives: A polymorphism in the promoter region of the IL-6 gene would influence the level of IL-6 expression in patients with HCV, resulting in a pro-inflammatory response. Few studies have shown the association between -174G>C (rs1800795) and -1363G>T (rs2069827) polymorphisms and HCV infection, and their results have been contradictory. There are no data published in our population to study...
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