Article
Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan.
Journal of infection in developing countries - 4 Jul 2011
Afzal Muhammad Sohail, Tahir Sadia, Salman Amna, Baig Tahir Ahmed, Shafi Talha, Zaidi Najm Us Sahar Sadaf, Qadri Ishtiaq
Abstract excerpt
INTRODUCTION: Hepatitis C virus (HCV) commonly causes a chronic infection but few of patients are able to clear the virus naturally. Interleukin-10 (IL-10) is an anti-inflammatory cytokine that can suppress the immune response against HCV. Interindividual variations in IL-10 production are genetically contributed by polymorphisms within the IL-10 promoter region. This study aimed to investigate the association of...
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