Article
An interleukin-6 gene promoter polymorphism is associated with polycystic ovary syndrome in South Indian women.
Journal of assisted reproduction and genetics - 1 Dec 2013
Tumu Venkat Reddy, Govatati Suresh, Guruvaiah Praveen, Deenadayal Mamata, Shivaji Sisinthy, Bhanoori Manjula
Abstract excerpt
PURPOSE: Polycystic ovary syndrome (PCOS) is a most common endocrine disorder of reproductive age women. Interleukin-6 is involved in the pathophysiological characteristics associated with polycystic ovary syndrome (PCOS). The-174 G/C IL-6 gene promoter region single nucleotide polymorphism (SNP) may influence or modulate gene function and/or transcriptional efficiency. The current study was aimed to evaluate the...
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