Article
IL-6 -174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma.
Omics : a journal of integrative biology - 1 Mar 2011
Giannitrapani Lydia, Soresi Maurizio, Giacalone Antonio, Campagna Maria Elisa, Marasà Marta, Cervello Melchiorre, Marasà Salvatore, Montalto Giuseppe
Abstract excerpt
Recently, a link between high levels of circulating IL-6 and hepatocellular carcinoma (HCC) has been proposed. In addition, single nucleotide polymorphisms (SNPs) in the promoter region of the IL-6 gene have been reported to be related to several inflammatory-related conditions, including cancer. The purpose of this article is: (1) to evaluate the frequencies of SNPs in the IL-6 promoter region at position -174...
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